◆ AteloGene addresses the challenges of in vivo experiments

AteloGene is a transfection reagent consisting of atelocollagen, a highly biocompatible material with nearly 40 years of clinical use as a medical device. It enables nucleic acid delivery without liposomes or viral vectors, thus reducing the burden of internal procedures while facilitating in vivo experiments with suppressed toxicity and immunogenicity. It enables the in vivo delivery of diverse nucleic acids, including siRNA, miRNA, and antisense oligonucleotides.

▼ Achieve the reagent preparation in just 5 minutes

Tedious reagent preparation for in vivo experiments are time consuming and feels frustrating? AteloGene only requires mixing with your nucleic acid, thus achieving the preparation in just 5 minutes. This enables you to make efficient use of your invaluable time to conduct experiments (Excluding a 10-minute waiting period during inversion mixing).

▼ Reduce administration frequency by ~70%

In vivo experiments often require weekly evaluations over a long period, in which procedural variability can affect the results. AteloGene gels at the injection site provide sustained nucleic acid release for approximately one week. This sustained release reduces the administration frequency by ~70% .

(Based on a comparison of reagents from three companies requiring administration every 2–3 days and AteloGene Local Use “Quick Gelation” requiring administration every 7 days)

▼ Save research costs by over ¥1 million

The advantage of less number of administrations directly leads to lower usage of transfection reagents and expensive nucleic acids. This saves over ¥1 million in research costs, thus allowing more experiments to be conducted within the same budget and imparting research flexibility.（Comparison based on administering reagents from three companies, administered systemically every 2–3 days at an average cost of ¥340,000/250 nmol for in vivo siRNA, and AteloGene Local Use “Quick Gelation,” administered once every 7 days, for one month each.）

▼ Proven track record in various disease models

AteloGene has been used for numerous studies to date and contributed to many publications. We received comments from users: With its extensive publication record, we used it with confidence.

Why wouldn’t you try AteloGene for your next in vivo experiment?

A tutorial video, including efficacy data, can be viewed by clicking the button below.

Exhibition Information

We plan to exhibit at the following conferences in December.
Please visit us at the venue to see our atelocollagen products, including AteloGene.

The 48th Annual Meeting of the Molecular Biology Society of Japan

Dates: December 3 (Wed.)– 5(Fri.), 2025

Venue: Pacifico Yokohama, Exhibition Hall

Booth: 146 (Enter via Hall A entrance near Daily Yamazaki, then straight ahead on the left)