Atelocollagen Honeycomb Sponge scaffold for nerve and vascular research | Koken Co., Ltd.

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  • CSH-96

  • CSH-10

Atelocollagen, Honeycomb Sponge

Outline

Honeycomb sponge and Honeycomb disc 96 are sponge shaped type I  atelocollagen scaffolds and have a honeycomb-like porous structure and high pore density. This honeycomb structure enables facile supply of nutrients to cells and easy excretion of waste products.

What is Atelocollagen?

Applications

  • 3D culture

  •  Cell transplantation

  • Sustained release carrier

Features

  • The honeycomb structure facilitates the access of nutrients to the cultured cells and the removal of waste products from the sponge, allowing cells to proliferate within the sponge.

  • Cells are easily harvested by collagenase treatment.

  • It is biodegradable and suitable for cell transplantation

Type of collagen

Bovine hide derived atelocollagen

  • Stereo microscope image of CSH-96

  • Stereo microscope image of CSH-10

  • SEM image of Honeycomb sponge

  • SEM image of fibroblasts seeded in a Honeycomb sponge

Cat. No. Product Packaging Price
CSH-10 Atelocollagen, Honeycomb sponge Sterilized
Size: approximately 3×3×2 mm/sponge
Total surface area: about 2,000 cm²/g
Weight per volume: 12-13 mg/mL
Pore size: 200-400 μm
100 mg/bottle Visit distributor’s
web page
CSH-96 Atelocollagen, Honeycomb Disc 96 Sterilized
Size : φ6mm×2 mm
Pore size: 200-400 μm
25 pcs/bottle Visit distributor’s
web page

Storage: Room temperature  For research use only.

Click here for frequently asked questions about Honeycomb sponge

Use case

References

  • Nerve, Muscle,
    Blood vessels
  • Bone, Tooth, Cartilage
  • Miscellaneous
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      Stem Cells. 2017 Mar;35(3):641-653. PMID: 27862629
    • p27(Kip1) and p21(Cip1)-independent proliferative inhibition of vascular smooth muscle cells cultured in type-I collagen matrix honeycombs.
      Uchida M, Suzuki S, Suzuki T, Ishii I.
      Microvasc Res. 2016 Jan;103:36-40. PMID: 26522285
    • A 3D nanofibrous hydrogel and collagen sponge scaffold promotes locomotor functional recovery, spinal repair, and neuronal regeneration after complete transection of the spinal cord in adult rats.
      Kaneko A, Matsushita A, Sankai Y.
      Biomed Mater. 2015 Jan 13;10(1):015008. PMID: 25585935
    • Bone marrow stromal cells combined with a honeycomb collagen sponge facilitate neurite elongation in vitro and neural restoration in the hemisected rat spinal cord.
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