| Substances used in combination with atelocollagen |
Application |
Paper information |
| Decellularized tissues (cortical bone, bone marrow, and cartilage) |
Decellularized tissue, which was processed into powder, mixed with atelocollagen, and adipose-derived stem cells were cultured in 3D in collagen gels. |
Induction of osteogenic differentiation by the extracellular matrix of fetal bone tissues and adult cartilage.
Negishi J, Tanaka D, et al. Tissue Cell. 2024 Jul 17;90:102475. PMID: 39059134. |
| Cisplatin derivatives and transplatin derivatives |
These derivatives were mixed with atelocollagen and used to coat a culture substrate and culture fibroblast. Renal tubular epithelial cells were also cultured in three dimensions within the gel. |
A Transparent and Injectable Biomaterial Prepared by Mixing Collagen and Anti-Cancer Platinum Derivatives.
Ichise SF, Koide T. Macromol Biosci. 2024 Jun;24(6):e2300553. PMID: 38459799. |
| Magnetic anionic liposomes |
These liposomes were complexed with atelocollagen and loaded onto mesenchymal stem cells to magnetize them. They were subsequently administered via the tail vein into a subcutaneous tumor model. |
Efficient Liposome Loading onto Surface of Mesenchymal Stem Cells via Electrostatic Interactions for Tumor-Targeted Drug Delivery.
Kono Y, et al. Biomedicines. 2023 Feb 14;11(2):558. PMID: 36831094. |
| Hydroxyapatite + alginic acid (+ sericin and + chitosan) |
Granules composited with atelocollagen were fabricated and used to evaluate the sustained release of ibuprofen and to culture osteosarcoma cells. |
Biomimetic Apatite/Natural Polymer Composite Granules as Multifunctional Dental Tissue Regenerative Material.
Kołodziejska B, et al. Int J Mol Sci. 2023 Nov 25;24(23):16751. PMID: 38069072. |
| Genipin |
This substance was mixed with atelocollagen to prepare gels of different stiffness where lung cancer cells and mesenchymal stem cells were cultured. |
Stiffness-Modulation of Collagen Gels by Genipin-Crosslinking for Cell Culture.
Ishihara S, et al. Gels. 2023 Feb 10;9(2):148. PMID: 36826318. |
| Polyrotaxane |
The atelocollagen gel was cross-linked with polyrotaxane, and fibroblasts were cultured on the gel. |
Post-Cross-Linking of Collagen Hydrogels by Carboxymethylated Polyrotaxanes for Simultaneously Improving Mechanical Strength and Cell Proliferation.
Tamura A, et al. ACS Biomater Sci Eng. 2022 Feb 14;8(2):588-597. PMID: 34994537. |
| P(LLA-CL): poly (L-lactic acid)-co-poly(ϵ-caprolactone) + polyaniline |
The fibers prepared by electrospinning the mixture with atelocollagen were formed into a tube and transplanted into the cut site of the sciatic nerve along with mesenchymal stem cells. |
Bioactive Nanofiber-Based Conduits in a Peripheral Nerve Gap Management-An Animal Model Study.
Dębski T, et al. Int J Mol Sci. 2021 May 25;22(11):5588. PMID: 34070436. |
Titanium dioxide
|
Titanium dioxide nanotubes were coated with atelocollagen by electrophoretic deposition, and gingival epithelial cells were cultured on them. |
Establishment of perpendicular protrusion of type I collagen on TiO2 nanotube surface as a priming site of peri-implant connective fibers.
Nojiri T, et al. J Nanobiotechnology.2019 Mar 1;17(1):34. PMID: 30823919.
|
| Alginate |
A two-layered cell fiber was created with atelocollagen containing myoblasts on the inside and alginate on the outside, and then cultured with cyclic stretch. |
Effect of Cyclic Stretch on Tissue Maturation in Myoblast-Laden Hydrogel Fibers.
Bansai S, et al. Micromachines (Basel). 2019 Jun 15;10(6):399. PMID: 31208059. |
| Hyaluronic acid |
A sponge was made by mixing hyaluronic acid with atelocollagen, and fibroblasts were cultured on it. Then, it was transplanted into the wound of a mouse. |
Development of Stabilized Growth Factor-Loaded Hyaluronate- Collagen Dressing (HCD) matrix for impaired wound healing.
Choi SM, et al. Biomater Res. 2016 Apr 1;20:9. PMID: 27042331. |
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