Coating only? Four key applications you should know –Various uses of Atelocollagen– Four key applications you should know –Various uses of Atelocollagen– | Koken Co., Ltd.

AteloSeriesCollagen for Cell Culture and RNAi Techonology

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Coating only? Four key applications you should know –Various uses of Atelocollagen–

15 April 2025

 

 

 

 

Coating only? Four key applications you should know

-Various uses of Atelocollagen-

 

This newsletter is intended for those who think that “collagen is used only for coating cultureware.” 

 

KOKEN manufactures research products, primarily atelocollagen, and medical devices at our domestic factory. We have numerous research products that for at least 22 applications. So why not take this opportunity to learn about some of these applications that may allow you to achieve your research goals?

 3D Culture 

3D Ready Atelocollagen

This product enables anyone in your lab to readily establish stable 3D cultures. Experiments with as many as 240 wells for a 96-well plate can be conducted for approximately ¥10,000.

 

If you are planning to transplant 3D-cultured cells, sponge-like products are also available.

 

 Co-culture 

FibColl®Atelocollagen Inserts 24

Have you ever been concerned about the permeability of the insert material during interaction experiments or permeability tests? FibColl® does not require coating, and its pores do not become clogged. 

 

For contact coculture using gels that facilitate cell migration, solution-type products are available.

 

Cell Transplantation・Sustained Compound Release

3D Honeycomb Boosted

It is possible to scale up a 96-well plate cell culture approximately 100-fold to10⁶ cells. This enables transplantation, while maintaining cell adhesion, without the need to collect cells. 

 

High-concentration solutions are available for sustained release and injectable cell transplantation, and membrane-like products are available for cell sheet transplantation.

 

 

in vivo Transfection

AteloGene® Local Use “Quick Gelation”

With its sustained release properties, AteloGene® can reduce the frequency of administration by up to approximately 70%, reduce the variability from administration techniques, and potentially save your lab over ¥1 million.*


AteloGene® for Systemic Use is also available for systemic delivery via the tail vein or intraperitoneal administration.

*Comparison of the average cost of reagents from three companies that administer in vivo siRNA (priced at ¥340,000/250 nmol) systemically every 2–3 days versus AteloGene® QG administered locally once every 7 days, over one month. Refers to the variability in technique for each administration during repeated dosing.

 

Exhibition information

We plan to participate in the upcoming cosmetic exhibition in May 2025. Please visit us at the venue to explore our atelocollagen products, which are suitable for creating epidermal and full-thickness skin models.

CITE Japan 2025 (12th Cosmetic Ingredients & Technology Exhibition Japan)
Date: May 14 (Wednesday) – May 16 (Friday), 2025
Venue: Pacifico Yokohama
Booth: B19–18

Exhibitor Technical Presentation (Introduction of Cosmetic Ingredients)
Date: May 16 (Friday), 2025
Time: 11:45 am – 12:15 pm
Venue: Pacifico Yokohama North G303
Title: Decoding the Secrets of Selecting Collagen: From Concept to Form